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Chair Jeffrey Atkinson Professors Emeriti Ian D. Brindle, Martin S. Gibson, J.S. Hartman, Richard R. Hiatt, David C. Moule, Mary Frances Richardson, S.M. Rothstein Professors Jeffrey Atkinson, Tomas Hudlicky, Georgii Nikonov, Andrew G. Reynolds, Art van der Est Associate Professors Travis Dudding, Heather L. Gordon, Martin Lemaire, Costa Metallinos, Melanie Pilkington, Theocharis Stamatatos, Hongbin (Tony) Yan Assistant Professor Feng Li Adjunct Professors Christopher H. Marvin, Victor Snieckus, Lydia Chen Adviser Heather L. Gordon Senior Demonstrators Roger McLaughlin, Sergio Paone, Paul Zelisko Mass Spectrometry and Analytical Instrumentation Technologist Liqun Qiu NMR Technologist Razvan Simionescu Director, Co-operative Programs Cara Krezek Co-operative Program Co-ordinator Travis Dudding |
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Administrative Assistant Marie Harris 905-688-5550, extension 3406 CRN 411 Chemistry is the study of matter and its interactions with various forms of energy. Brock students are involved in the analysis, synthesis and purification of substances, determining their structures and properties and explaining the mechanisms of processes. Our programs stress chemical principles and practice through research in organic, inorganic, analytical, physical and theoretical chemistry, with a strong emphasis on the interdisciplinary fields of bio-inorganic and bio-organic chemistry and chemical biophysics. Research interests of the department include development of new chiral ligands, organometallic reagents, and methods for asymmetric synthesis, green chemistry including bacterial dioxygenase-mediated degradation of aromatics, new approaches in natural product synthesis emphasizing morphine alkaloids, design and synthesis of fluorinated inhalation anesthetic agents and unnatural oligo-saccharide conjugates, ligand design and crystal engineering aimed at self-assembly of novel molecule-based materials, organic electrochemistry, energetics of photosynthesis studied by time-resolved electron spin resonance of short-lived paramagnetic intermediates, nuclear magnetic resonance spectroscopy, organometallic mass spectrometry, quantum and computational chemistry, pesticide and trace element analysis, protein affinity labelling and protein-lipid interactions, and structure-activity correlations of anticancer pharmaceuticals. The Honours program in Chemistry is designed to give the student a broad knowledge of chemistry as well as depth in areas in which the student is most interested. A research project must be successfully completed and a thesis written as part of the requirements for an Honours degree. The Honours program and certain combined Honours programs listed below, when taken with CHEM electives, satisfy the requirements for membership in the Chemical Institute of Canada and are the normal requirements for admission to graduate school in chemistry. The Chemistry Co-op program combines academic and work terms over a four and one half year period. Students spend two years in an academic setting, where they acquire the necessary background prior to taking the first work placement. Successful completion of courses in the core areas of Chemistry provides the necessary academic background for the work experience. In addition to the current fees for courses in academic study terms, Chemistry Co-op students are assessed an annual administrative fee (see the Schedule of Fees). Eligibility to continue in the Co-op program is based on the student's major average and non-major average. A student with a minimum 70 percent major average and a minimum 60 percent non-major average will be permitted to continue. A student with a major average lower than 70 percent will not be permitted to continue in the Chemistry Co-op program, but may continue in the non Co-op Chemistry stream. For further information, see the Co-op Programs section of the Calendar, and contact the Department of Chemistry. All students in the Co-operative Education program are required to read, sign and adhere to the terms of the Student Regulations Waiver and Co-op Student Manuals (brocku.ca/co-op/current-students/co-op-student-manuals) as articulated by the Co-op Programs Office. In addition, eligibility to continue in the co-op option is based on the student's major average and non-major average, and the ability to demonstrate the motivation and potential to pursue a professional career. Each four-month co-operative education work term must be registered. Once students are registered in a co-op work term, they are expected to fulfill their commitment. If the placement accepted is for more than one four-month work term, students are committed to complete all terms. Students may not withdraw from or terminate a work term without permission from the Director, Co-op Program Office. The requirement for graduation with a Chemistry (Honours) degree is a minimum 70 percent major average and a minimum 60 percent non-major average. The Chemistry Co-op program designation will be awarded to those students who have honours standing and who have successfully completed a minimum of twelve months of Co-op work experience. The equipment available in the Mackenzie Chown and Cairns Family Health and Bioscience Research Complexes is actively used for both teaching and research. Undergraduate students gain hands-on experience in operating modern equipment for separating of complex mixtures, determining molecular structures, and making quantitative measurements. Newer equipment is computer-controlled and is connected to the University's Ethernet backbone. Student and faculty researchers have access to cluster platform systems, housed at Brock Univeristy and other SHARCNet academic institutions. Instrumentation includes 300, 400 and 600 MHz NMR cryospectrometers for high-resolution solution and solids studies. Mass spectrometry facilities include a Thermo DFS high resolution mass spectrometer with EI, CI and FAB ion sources. It is equipped with a high performance capillary GC system. The lab also contains a Bruker HCT Ultra LC/MS system with ESI and APCI interfaces and a BrukerAutoflex II TOF/TOF MALDI system. For X-ray crystallography, a Bruker Apex II CCD diffractometer, equipped with an Oxford low temperature device, is available for the collection of single crystal data. A number of spectroscopic instruments are available in the research laboratories including time-resolved EPR, ICP and ICP/MS, FTIR, UV/Visible, fluorescence cuvette and microplate fluorimeters. There are several chromatography systems for HPLC, FPLC and capillary GC analysis. A state-of-the-art biotechnology research lab was recently equipped for biochemistry and microbiology work. This instrumentation is augmented by a range of modern facilities available through the Cool Climate Oenology and Viticulture Institute, which support work in biochemistry, especially work involving proteins, nucleic acids, yeasts and bacteria. Students should consult the Department Chair when planning years 3 and 4 of the BSc (Honours) and BSc with Major programs, or year 3 of the BSc (Pass) program. In addition to its own programs, the Chemistry department participates in combined major programs with five other departments/centres and is also a major participant in the Biochemistry, Biotechnology, and Oenology and Viticulture programs. |
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Students admitted to the Chemistry Co-op program must follow an approved program pattern. The most common pattern is listed below. For other approved patterns, consult the Co-op Office. Year 1
Year 2
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This program differs from the Honours program in that honours standing is not required for entry into year 4, and year 4 does not include the research project and thesis courses (CHEM 4F90 and 4F91). Combined majors should consult the Chair. Year 1
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Satisfactory completion of the first three years of the Honours program entitles a student to apply for a Pass degree. |
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Consult the Biochemistry calendar entry for a listing of courses and program requirements. |
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Consult the Biotechnology calendar entry for a listing of courses and program requirements. |
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The Department of Chemistry and the Faculty of Education co-operate in offering two Concurrent BSc (Honours)/BEd programs. The Chemistry BSc (Honours)/BEd programs combines the BSc Honours program or BSc Integrated Studies Honours program with the teacher education program for students interested in teaching at the Intermediate/Senior level (grades 7-12) and at the Junior/Intermediate level (grades 4-10). Refer to the Education - Concurrent BSc (Honours)/BEd (Intermediate/Senior) or Education - Concurrent BSc Integrated Studies (Honours)/BEd (Junior/Intermediate) program listings for further information. |
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Combined Honours and Pass programs can be taken in Chemistry/Biology, Chemistry/Computer Science (Honours only), Chemistry/Earth Sciences, Chemistry/Mathematics and Chemistry/Physics. In most of the combined major programs a research project must be successfully completed and a thesis written as part of the requirements for an Honours degree. |
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Honours Year 1
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Year 3
Year 4
Pass Satisfactory completion of the first three years of the Honours program entitles a student to apply for a Pass degree. |
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Honours Year 1
Year 2
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Pass Satisfactory completion of the first three years of the Honours program entitles a student to apply for a Pass degree. |
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Consult the Biological Sciences entry for a listing of program requirements. |
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Consult the Computer Science entry for a listing of program requirements. |
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Consult the Earth Sciences entry for a listing of program requirements. |
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Students in other disciplines may obtain a minor in chemistry within their degree program by completing the following courses with a minimum 60 percent average:
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Under the Agreement, Brock University will admit graduates of Mohawk College who have completed the Chemical Engineering Technology (533) diploma program with a minimum 78 percent overall average to its Honours Bachelor of Science program in Chemistry with 6.5 credits in advanced standing. |
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The Department of Chemistry offers opportunities for graduate study leading to a MSc or PhD degree. Graduate programs emphasize independent research by students in a wide variety of chemical fields reflecting research interests of individual faculty. For further information, including faculty interests, see the current Graduate Calendar or the Department of Chemistry's website. |
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Note that not all courses are offered in every session. Refer to the applicable term timetable for details. # Indicates a cross listed course * Indicates a primary offering of a cross listed course |
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Students must check to ensure that prerequisites are met. Students may be deregistered, at the request of the instructor, from any course for which prerequisites and/or restrictions have not been met. CHEMISTRY COURSES Introductory Chemistry Fundamental principles of chemistry. Topics include atomic structure and the periodic table, names and formulas of chemical compounds, principles of chemical bonding, types of chemical reactions, and basic chemical calculations. Tutorials emphasize the development and practice of problem solving skills. Lectures, 3 hours per week; lab, tutorial and problems solving session, 3 hours per week. Note: open to students with less than 70 percent 4U/M chemistry or equivalent who are enrolled in a program leading to a BSc degree, or with permission from the Department. CHEM 1P00 is designed to assist those with insufficient background in chemistry to succeed in CHEM 1P91 and 1P92. Students with less than 70 percent in 4U/M chemistry, or who have not taken an advanced high school chemistry course are allowed to take CHEM 1P91 and 1P92 instead of CHEM 1P00 by permission of the Department if they pass a written test of basic chemistry knowledge, to be administered before classes begin. Materials fee required. Chemical Principles and Properties I Stoichiometry, inorganic and organic reactions, quantum mechanics, molecular structure and bonding, solutions and their properties, thermochemistry and gas laws. Lectures, 3 hours per week; tutorial, 1 hour alternating weeks; plus a minimum of five 3-hour labs per term. Restriction: open to CHEM (single or combined), CHEN, BCHM, BIOL, BION, BMED, BPHY, BTEC, CAST, ERSC (single or combined), ERSN, EVGN, EVGS, HEAR, MSCI, NEUN, NEUR, OEVI, PHYN, PHYS majors, Sciences (general) students and CHEM minors until date specified in Registration guide. After that date open to CHEM (single or combined), CHEN, BCHM, BIOL, BION, BMED, BPhEd (Honours)/BEd (Intermediate/Senior), BPHY, BSc (Honours)/BEd (Intermediate/Senior), BSc (Honours)/BEd (Junior/Intermediate), BTEC, CAST, ERSC (single or combined), ERSN, EVGN, EVGS, HEAR, MSCI, NEUN, NEUR, OEVI, PHYN, PHYS majors, Sciences (general) students and CHEM minors until date specified in Registration guide. Prerequisite(s): a minimum 70 percent grade in 4U/M chemistry (or equivalent course), CHEM 1P00 or permission of the Department. Note: materials fee required. Completion of this course will replace previous assigned grade and credit obtained in CHEM 1F92 and 1P90. Chemical Principles and Properties II Molecular structure, shapes, and behaviour of molecules emphasizing organic compounds, bonding and intermolecular interactions, the states of matter, chemical equilibrium, titrations, entropy, free energy, electrochemistry, and reaction rates. Lectures, 3 hours per week; tutorial, 1 hour alternating weeks; plus a minimum of five 3-hour labs per term. Restriction: open to CHEM (single or combined), CHEN, BCHM, BIOL, BION, BMED, BPHY, BTEC, ERSC (single or combined), ERSN, EVGN, EVGS, HEAR, MSCI, NEUN, NEUR, OEVI, PHYN, PHYS majors, Sciences (general) students and CHEM minors until date specified in Registration guide. After that date open to CHEM (single or combined), CHEN, BCHM, BIOL, BION, BMED, BPhEd (Honours)/BEd (Intermediate/Senior), BPHY, BSc (Honours)/BEd (Intermediate/Senior), BSc (Honours)/BEd (Junior/Intermediate), BTEC, ERSC (single or combined), ERSN, EVGN, EVGS, HEAR, MSCI, NEUN, NEUR, OEVI, PHYN, PHYS majors, Sciences (general) students and CHEM minors until date specified in Registration guide. Prerequisite(s): CHEM (1P90) or 1P91. Note: materials fee required. Completion of this course will replace previous assigned grade and credit obtained in CHEM 1F92. Introduction to Modern Physical Chemistry Phase equilibrium; gas phase kinetics; electronic structure of atoms and molecules; interaction of light with matter. Lectures, 3 hours per week; tutorial, 2 hours per week; plus a minimum of six 3-hour labs. Prerequisite(s): CHEM 1P91 and 1P92 (1F92); one of MATH 1P01 and 1P02, MATH 1P05 and 1P06 (preferred), MATH 1P97. Note: CHEM 2P63 recommended. Principles of Organic Chemistry I Introduction to the principles and techniques of organic chemistry; correlation of reactions and physical properties of organic compounds with structure and energetic concepts. Introduction to applications of spectroscopy in organic chemistry and biochemistry. Selected experiments in organic preparations and techniques. Lectures, 3 hours per week; tutorial 1.5 hours per week; lab, 3 hours per week. Restriction: open to CHEM (single or combined), BCHM, BMED, BPHY, BTEC, NEUN, NEUR, OEVI majors and CHEM minors until date specified in Registration guide. After that date open to CHEM (single or combined), BCHM, BMED, BPHY, BSc (Honours)/BEd (Intermediate/Senior), BSc (Honours)/BEd (Junior/Intermediate), BTEC, NEUN, NEUR, OEVI majors, Sciences (general) students and CHEM minors until date specified in Registration guide. Prerequisite(s): CHEM 1P91 and 1P92 (1F92) (minimum 60 percent) or permission of the instructor. Note: materials fee required. Principles of Organic Chemistry II Introduction to aromatic molecules and electrophilic aromatic substitution reactions. Chemistry of natural products, their origin and biological significance. Topics include concepts of carbonyl and carbohydrate chemistry, DNA and an introduction to amino acids and proteins. Selected experiments in organic synthesis, and characterization and analysis. Lectures, 3 hours per week; tutorial 1.5 hours per week; lab, 3 hours per week. Restriction: open to CHEM (single or combined), BCHM, BMED, BPHY, BTEC, NEUR, OEVI majors and CHEM minors until date specified in Registration guide. After that date open to CHEM (single or combined), BCHM, BMED, BPHY, BSc (Honours)/BEd (Intermediate/Senior), BSc (Honours)/BEd (Junior/Intermediate), BTEC, NEUR, OEVI majors, Sciences (general) students and CHEM minors until date specified in Registration guide. Prerequisite(s): CHEM 2P20. Note: materials fee required. Principles of Inorganic Chemistry Basic principles of coordination chemistry. Chemistry and reactions in aqueous solutions; structure and bonding in simple compounds. Introduction to bioinorganic chemistry highlighting the overlap between inorganic chemistry and biology. Survey of the periodic table stressing periodicity of chemical behaviour. Lectures, 3 hours per week; plus a minimum of six 3-hour labs. Prerequisite(s): CHEM 1P91 and 1P92 (1F92). Note: materials fee required. Introduction to Analytical Chemistry Introduction to analytical methods such as volumetric methods (acid-base, complexometric, precipitation and redox titrations), electroanalytical techniques (potentiometry), spectrophotometry, solvent extraction and chromatography. Statistical treatment of analytical data, chemical equilibria, pH, buffers and chemical activities. Lectures, lab, 6 hours per week. Prerequisite(s): CHEM 1P91 and 1P92 (1F92). Note: materials fee required. Introduction to Biophysical Chemistry (also offered as BTEC 2P63) Physical chemistry as applied to biological sciences. Introductory thermodynamics, kinetics, equilibria, and transport phenomena as applied to proteins, biological membranes and other biological systems. Laboratory work includes kinetic measurements, equilibrium constant measurements and protein purification and characterization. Lectures, lab, 6 hours per week. Restriction: open to CHEM (single or combined), CHEN, BCHM, BPHY, BTEC, OEVI, Sciences (general) students and CHEM minors until date specified in Registration guide. After that date open to CHEM (single or combined), CHEN, BCHM, BPHY, BSc (Honours)/BEd (Intermediate/Senior), BSc (Honours)/BEd (Junior/Intermediate), BTEC, OEVI, Sciences (general) students and CHEM minors until date specified in Registration guide. Prerequisite(s): CHEM 1P91 and 1P92 (1F92); one of MATH 1P01 and 1P02, MATH 1P05 and 1P06 (preferred), MATH 1P97. Note: materials fee required. Undergraduate Research Undergraduate research project carried out either in the department under the supervision of a faculty member or as an employee in a chemical industry or other suitable laboratory. Restriction: open to CHEM (single or combined) majors and permission of the Department. Structure and Reactivity of Organic Molecules Methods for functional group manipulation including oxidation, reduction and the use of protecting groups in organic chemistry. General methods for carbon-carbon bond formation emphasizing three dimensional structure and mechanism. Modern methods of asymmetric synthesis. Selected experiments in synthetic organic chemistry and the handling of air and water sensitive reagents. Lectures, lab, 6 hours per week. Prerequisite(s): CHEM 2P21 or permission of the Department. Note: CHEM 3P40 recommended. May be taken concurrently. Organic Reactions The chemistry of amines, heterocyclic and heteroaromatic compounds. Pericyclic reactions and reactive intermediates. Molecular rearrangements, peptide synthesis and protecting groups, design of organic synthesis. Introduction to organic photochemistry and the chemistry of carbenes. Lectures, lab, 6 hours per week. Prerequisite(s): CHEM 3P20. Main Group Inorganic Chemistry Systematic inorganic and organometallic chemistry of the main group elements, emphasizing structure, bonding and reactivity in inorganic and organometallic compounds. Selected experiments in inorganic and organometallic synthesis; use of modern structural methods for determination of composition, structure and bonding. Lectures, lab, 6 hours per week. Prerequisite(s): CHEM 2P32. Note: CHEM 3P40 recommended. May be taken concurrently. Transition Metal Chemistry d-Block metal chemistry. Magnetic and electronic properties of metal complexes under different coordination geometries and environments. First row transition metals, their properties, chemical reactivity and applications in materials science, magnetism, optics and nanotechnology. Organometallic compounds of d-block elements and their applications in catalysis. Lectures, lab, 6 hours per week. Prerequisite(s): CHEM 3P30. Note: CHEM 3P40 recommended. May be taken concurrently. Spectroscopic Techniques for Structure Elucidation Use of instrumental methods for the determination of structures of molecules. Techniques will include mass spectrometry, nuclear magnetic resonance spectroscopy, covered Fourier transform infrared spectroscopy, visible and UV spectroscopy, computerized data manipulation. Lectures, tutorial, 6 hours per week. Restriction: students must have a minimum of 9.0 overall credits. Prerequisite(s): CHEM 2P20. Instrumental Methods for Quantitative Analysis Modern instrumentation and their applications to quantitative analysis of atomic and molecular species. Separation methods such as gas, liquid and supercritical fluid chromatography, and capillary electrophoresis. Techniques such as UV-vis absorption, atomic absorption, atomic emission, atomic fluorescence and mass spectrometry. Emphasis on sample preparation and cleanup, and quality assurance/quality control. Lectures, lab, 6 hours per week. Restriction: students must have a minimum of 9.0 overall credits. Prerequisite(s): CHEM 2P42. Note: materials fee required. Quantum Chemistry Schrodinger equation, solution of the harmonic oscillator problem, hydrogen atom, angular momentum theory, variational method with applications to atomic and molecular systems, molecular orbital theory and simple group theory. Introduction to a procedural programming language. Lectures, 3 hours per week; lab, 2 hours per week; tutorial, 1 hour per week. Prerequisite(s): CHEM 2P12. Atomic and Molecular Structure and Spectroscopy Group theory and theory of electro-magnetic radiation and spectroscopic transitions. Rotational and vibrational spectroscopy (Microwave, IR, Raman); atomic and molecular electronic spectroscopy (UV/Visible); magnetic resonance (NMR, EPR). Lectures, lab, 6 hours per week. Prerequisite(s): CHEM 3P51. Industrial Chemistry Principles and practice of industrial chemistry. Survey of the chemical industry, pollution control, plant design, corrosion and similar topics. Selected industrial processes will be discussed in detail. Tours of chemical plants and industrial laboratories. Lectures, 3 hours per week; seminar, plant tour, 3 hours per week. Prerequisite(s): one and one-half credits from CHEM 2P12, 2P20, 2P21, 2P32, 2P42, 2P63. Note: steel-toed safety boots may be required on plant tours. Organic Chemistry in Industry Industrial organic chemicals including raw materials, base and commodity chemicals, and chemicals with specialized applications, such as dyes and pigments, fluorophores, agrochemicals, surfactants, and pharmaceuticals. Lectures, seminar, 3 hours per week. Prerequisite(s): CHEM 2P20, 2P21 and 2P63. Bio-organic Chemistry (also offered as BTEC 3P62) Mechanistic description of the biosynthesis and metabolism of natural products including alkaloids, terpenes and acetate-derived compounds. Selected examples of biologically/medicinally active classes of natural products along with their physiological modes of activity. Lectures, 3 hours per week. Prerequisite(s): CHEM 2P21. Protein and Nucleic Acid Chemistry (also offered as BTEC 3P93) Chemistry and structure of nucleic acids, proteins, and carbohydrates. Selected aspects of chemical synthesis and biosynthesis, including mechanisms of protein folding, post-translational modification, targeting, sequencing, detection techniques and biochemical/medical applications of these molecules. Lectures, lab, 6 hours per week. Prerequisite(s): CHEM 2P21. Note: materials fee required. Undergraduate Research Project Undergraduate research project carried out either in the department under the supervision of a faculty member or as an employee in a chemical industry or other suitable laboratory. Restriction: open to CHEM (single or combined) majors with 9.0 overall credits and permission of the Department. Research Project Experimental or theoretical research to be carried out under faculty supervision. Restriction: open to CHEM (single or combined) and BCHM majors with approval to year 4 (honours) and permission of the Chair. Prerequisite(s): CHEM 3P40 or 3P41. Corequisite(s): CHEM 4F91. Thesis The thesis incorporates the results of the research in CHEM 4F90 and forms the basis for a seminar to be presented by the student. Restriction: open to CHEM (single or combined) and BCHM majors with approval to year 4 (honours) and permission of the Chair. Prerequisite(s): CHEM 3P40 or 3P41. Corequisite(s): CHEM 4F90. Special Topics Tutorials, seminars, special projects or directed readings in an area of chemistry. Lectures/seminar/ tutorial, 3 hours per week. Restriction: open to CHEM (single or combined) majors with a minimum of 14.0 overall credits and permission of the Chair. Statistical Thermodynamics in Chemistry and Biology Ensembles, entropy, free energy, statistical mechanics of simple gases and solids, heat capacity, chemical equilibrium, substrate binding, water as a solvent, and polymers and biopolymers. Lectures, seminar, 3 hours per week. Prerequisite(s): CHEM 3P51. Biophysical Photochemistry Principles of light induced processes such as electron, energy and signal transfer and their role in biological systems. Marcus theory, Dexter and Foerster mechanisms of energy transfer. The optical and magnetic resonance spectroscopy of excited states. Lectures, 3 hours per week. Prerequisite(s): CHEM 3P40, 3P53 or permission of the instructor. Computational Chemistry: Applications in Biotechnology (also offered as BTEC 4P18) Structure-based drug design, molecular modelling, conformational search techniques, secondary and tertiary protein structure prediction, quantitative structure activity relationships and bioinformatics. Lectures, 3 hours per week. Restriction: students must have a minimum of 13.5 overall credits. Prerequisite(s): CHEM 2P12 or 2P63; three credits numbered 2(alpha)90 or above. Organic Reactions and Synthesis Organic reaction mechanisms. Named reactions and their use in synthesis. Review of basic physical organic principles. Emphasis on selectivity and stereochemistry in modern synthetic methods including organometallic reactions. Lectures, seminar, 3 hours per week. Prerequisite(s): CHEM 3P21. Organic Reactions and Mechanisms Topics include conformational analysis, introduction to transition state theory and the description of stereo and electronic control in organic reactions. Pertinent applications will be taken from the recent literature. Lectures, seminar, 3 hours per week. Prerequisite(s): CHEM 3P21. Organometallics in Organic Synthesis Use of organometallic reagents for organic transformations. Metalation and trans-metalation using organolithium, magnesium, cerium and zinc reagents; stable precursors and reactive intermediates in transition metal catalyzed organic reactions employing palladium, nickel, ruthenium, and other metals. Topics from recent literature involving applications to organic synthesis, emphasizing stereoselectivity. Lectures, seminar, 3 hours per week. Prerequisite(s): CHEM 3P20; CHEM 3P21 or 3P31. Toxicological Chemistry and Biochemistry (also offered as BTEC 4P26) Principles of toxicology. Key enzymes involved in the metabolism and biotransformation of xenobiotics. Actions of xenbiotics on nucleic acids, proteins and lipids. Biochemical mechanisms of the toxicity of selected xenobiotics such as toxins, common toxic chemicals, drugs and pesticides. Identification of xenobiotics in biological systems. Lectures, 3 hours per week. Restriction: students must have a minimum of 10.0 overall credits. Prerequisite(s): CHEM 2P21 or permission of the instructor. Enzyme and Co-enzyme Mechanisms (also offered as BTEC 4P27) Hydrolytic and other processes catalyzed by enzymes lacking non-protein prosthetic groups; transferase reactions involving biotin, pyridoxal phosphate, thiamine pyrophosphate, folic acid and cobalamin; oxidation mechanisms involving pyridine nucleotides, flavoenzymes, hydroperoxidases and oxgenases. Lectures, seminar, 3 hours per week. Prerequisite(s): CHEM 2P21, BCHM 3P01and 3P02. Bio-organic Chemistry: Carbohydrates and Nucleic Acids (also offered as BTEC 4P28) Topics include mono and oligosaccharides, preparative carbohydrate chemistry, neoglycoconjugates, immunochemistry of carbohydrates, nucleosides and nucleotides, oligonucleotide synthesis, medicinal chemistry of oligonucleotides, amino acids, protein structures, peptide chemistry and post-translational modifications. Lectures, 3 hours per week. Prerequisite(s): CHEM 2P21. Advanced Co-ordination Chemistry Bonding and electronic structure of transition metal coordination complexes through an application of symmetry properties and group theory tools. Topics include bonding, electronic structure and properties (ligand field theory), molecular magnetism, EPR properties. Prerequisite(s): CHEM 2P32 and 3P51. Advanced Inorganic and Organometallic Chemistry Continuation of CHEM 3P30 and 3P31 focusing on advanced topics of inorganic and organometallic chemistry of main group and transition metal elements, emphasizing the use of modern physical methods for determination of composition, structure and bonding of inorganic and organometallic compounds. Lectures, 3 hours per week. Prerequisite(s): CHEM 3P31 and 3P53. Note: CHEM 3P53 may be taken concurrently with permission of the instructor. Biological Inorganic Chemistry Overview of biological inorganic chemistry focusing on the uptake, transport and storage of metal ions, electron-transfer systems, hydrolytic enzymes, oxygen transport/activation, nitrogen metabolism and metallotherapeutics. Lectures, seminar, 3 hours per week. Restriction: students must have a minimum of 12.0 overall credits. Prerequisite(s): CHEM 2P21 and 2P32. Structure Determination by X-ray Crystallography X-ray diffraction by crystalline materials to determine the structures of small molecules. Topics may include crystal growth, selection and mounting, X-ray generation, crystal symmetry and space groups, X-ray diffraction, the phase problem, structure solution and refinement, and interpretation and presentation of structural data. Lectures, 3 hours per week. Prerequisite(s): CHEM 2P32; three CHEM credits numbered 2(alpha)90 or above. Note: CHEM 4P30 recommended. May be taken concurrently. Principles of Polymer Chemistry Polymer synthesis involving condensation, living anionic and cationic polymerization and atom transfer radical polymerization. Cross-linked and dendritic polymers and their properties, and the role played by polymers in biomedical applications such as drug delivery and implantable devices. Lectures, seminar, 3 hours per week. Prerequisite(s): CHEM 2P20 and 2P21. Note: CHEM 3P20 and 3P21 are recommended. Principles of Silicon Chemistry Chemistry of silicon in organic, organometallic and polymeric compounds emphasizing structure, bonding and reactivity. Applications of silicon in the biomedical field and the interaction with biomolecules. Lectures, 3 hours per week. Prerequisite(s): CHEM 2P20 and 2P21. Note: CHEM 2P32, 3P20 and 3P21 are recommended. Biophysical Techniques (also offered as BCHM 4P67 and BTEC 4P67) Modern instrumental methods of biotechnology emphasizing understanding theory. Development of newer technologies which utilize biological components. Topics include optical, X-ray and NMR techniques, separation techniques, hybridization assays, immunoassays, biosensors and mass spectral techniques; membrane chemistry. Lectures, seminar, 3 hours per week. Prerequisite(s): CHEM 2P21 and 2P63 or permission of the instructor. Library Research and Seminar Detailed study of the scientific literature under faculty supervision. Restriction: open to students in the BSc with Major Chemistry program with a minimum of 15.0 overall credits or permission of the Department. Note: the results of the study will be written up in a major essay and presented as a formal seminar. SCIENCE COURSES Science and Society I Basic questions and problems in understanding the nature of science in relation to current environmental issues and their impact on society. Most common scientific concepts and theories associated with major environmental problems facing the world today. Lectures, 3 hours per week; seminar, 1 hour alternate weeks. Note: for non-science majors. Co-ordinated through the Department of Chemistry. Science and Society II Introduction to interrelationships between science, technology and society. Topics include the nature of science and technology, genetic engineering, pharmaceutical industry and food additives. Lectures, 3 hours per week; seminar, 1 hour alternate weeks. Note: for non-science majors. Co-ordinated through the Department of Chemistry. Chemistry in Everyday Life Basic chemical knowledge needed to evaluate current controversies involving food, health, drug and energy issues. Note: offered online. Intended for non-science majors. Co-ordinated through the Department of Chemistry. CO-OP COURSES Work Placement I First co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. Work Placement II Second co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. Work Placement III Third co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. Work Placement IV Optional Co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. Work Placement V Optional Co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. Co-op Reflective Learning and Integration I Provide student with the opportunity to apply what they've learned in their academic studies through career-oriented work experiences at employer sites. Restriction: open to CHEM Co-op students. Prerequisite(s): SCIE 0N90. Corequisite(s): CHEM 0N01. Note: students will be required to prepare learning objectives, participate in a site visit, write a work term report and receive a successful work term performance evaluation. Co-op Reflective Learning and Integration II Provide student with the opportunity to apply what they've learned in their academics studies through career-oriented work experiences at employer sites. Restriction: open to CHEM Co-op students. Prerequisite(s): SCIE 0N90. Corequisite(s): CHEM 0N02. Note: students will be required to prepare learning objectives, participate in a site visit, write a work term report and receive a successful work term performance evaluation. Co-op Reflective Learning and Integration III Provide student with the opportunity to apply what they've learned in their academic studies through career-oriented work experiences at employer sites. Restriction: open to CHEM Co-op students. Prerequisite(s): SCIE 0N90. Corequisite(s): CHEM 0N03. Note: students will be required to prepare learning objectives, participate in a site visit, write a work term report and receive a successful work term performance evaluation. Co-op Reflective Learning and Integration IV Provide student with the opportunity to apply what they've learned in their academic studies through career-oriented work experiences at employer sites. Restriction: open to CHEM Co-op students. Prerequisite(s): SCIE 0N90. Corequisite(s): CHEM 0N04. Note: students will be required to prepare learning objectives, participate in a site visit, write a work term report and receive a successful work term performance evaluation. Co-op Reflective Learning and Integration V Provide student with the opportunity to apply what they've learned in their academics studies through career-oriented work experiences at employer sites. Restriction: open to CHEM Co-op students. Prerequisite(s): SCIE 0N90. Corequisite(s): CHEM 0N05. Note: students will be required to prepare learning objectives, participate in a site visit, write a work term report and receive a successful work term performance evaluation. Co-op Training and Development Framework for the development of learning objectives for individual work terms, for students in the co-op programs in the Faculty of Mathematics and Science. Includes orientation to the co-op experience, goal setting, career planning, résumé preparation and interview skills preparation. Lectures, presentations, site visits, 2 hours per week. Restriction: open to Science Co-op students. Note: see Director of Co-op Programs Office. |
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2017-2018 Undergraduate Calendar
Last updated: March 12, 2018 @ 01:09PM