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Chair Art van der Est Professors Emeriti Martin S. Gibson, Richard R. Hiatt, David C. Moule Professors Ian D. Brindle, J. Stephen Hartman, Tomas Hudlicky, Jack M. Miller, Andrew G. Reynolds, Mary Frances Richardson, Stuart M. Rothstein Associate Professors Jeffrey K. Atkinson, Heather L. Gordon, Melanie Pilkington, Art van der Est Assistant Professors Travis Dudding, Costa Metallinos Lecturer Roger L.J. McLaughlin Adjunct Professor Christopher H. Marvin Senior Demonstrators Gail Neff, Paul Zelisko Senior Demonstrator - Research Technician Donna Vukmanic Co-ordinator, Analytical Services T. R. B. Jones Director, Co-operative Programs Cindy Dunne Co-operative Program Co-ordinator Stuart M. Rothstein |
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Administrative Assistant Christine Skorski 905-688-5550, extension 3406 Mackenzie Chown E206 http://www.brocku.ca/chemistry Chemistry is the study of matter and its interactions with various forms of energy. Brock students are involved in the analysis, synthesis and purification of substances, determining their structures and properties and explaining the mechanisms of processes. Our programs stress chemical principles and practice through research in organic, inorganic, analytical, physical and theoretical chemistry, with a strong emphasis on the interdisciplinary fields of bio-inorganic and bio-organic chemistry and chemical biophysics. Research interests of the department include development of new chiral ligands, organometallic reagents, and methods for asymmetric synthesis, green chemistry including bacterial dioxygenase-mediated degradation of aromatics, new approaches in natural product synthesis emphasizing morphine alkaloids, design and synthesis of fluorinated inhalation anesthetic agents and unnatural oligo-saccharide conjugates, ligand design and crystal engineering aimed at self-assembly of novel molecule-based materials, organic electrochemistry, energetics of photosynthesis studied by time-resolved electron spin resonance of short-lived paramagnetic intermediates, nuclear magnetic resonance spectroscopy, organometallic mass spectrometry, quantum and computational chemistry, pesticide and trace element analysis, protein affinity labelling and protein-lipid interactions, and structure-activity correlations of anticancer pharmaceuticals. The Honours program in Chemistry is designed to give the student a broad knowledge of chemistry as well as depth in areas in which the student is most interested. A research project must be successfully completed and a thesis written as part of the requirements for an Honours degree. The Honours program and certain combined Honours programs listed below, when taken with CHEM electives, satisfy the requirements for membership in the Chemical Institute of Canada and are the normal requirements for admission to graduate school in chemistry. The Chemistry Co-op program combines academic and work terms over a four and one half year period. Students spend two years in an academic setting, where they acquire the necessary background prior to taking the first work placement. Successful completion of courses in the core areas of Chemistry provides the necessary academic background for the work experience. In addition to the current fees for courses in academic study terms, Chemistry Co-op students are assessed an annual administrative fee (see the Schedule of Fees). Eligibility to continue in the Co-op program is based on the student's major average and non-major average. A student with a minimum 70 percent major average and a minimum 60 percent non-major average will be permitted to continue. A student with a major average lower than 70 percent will not be permitted to continue in the Chemistry Co-op program, but may continue in the non Co-op Chemistry stream. For further information, see the Co-op Programs section of the Calendar, and contact the Department of Chemistry. The requirement for graduation with a Chemistry (Honours) degree is a minimum 70 percent major average and a minimum 60 percent non-major average. The Chemistry Co-op program designation will be awarded to those students who have honours standing and who have successfully completed a minimum of twelve months of Co-op work experience. The equipment available in the Mackenzie Chown Complex is actively used for both teaching and research. Undergraduate students gain hands-on experience in operating modern equipment for separating of complex mixtures, determining molecular structures, and making quantitative measurements. Newer equipment is computer-controlled and is connected to the University's Ethernet backbone. The department also has a variety of computers and UNIX workstations for advanced computation, data interpretation and molecular modelling. Instrumentation includes 300-and 600- MHz NMR cryospectrometers for high-resolution solution and solids studies. Mass spectrometry facilities include a high resolution machine with EI, CI and FAB ion sources, an ion trap ESI/LC/MS system, a MALDI/TOF spectrometer and two capillary GC/MS facilities. A number of spectroscopic instruments are available in the research laboratories including time-resolved EPR, ICP and ICP/MS, FTIR, UV/Visible, Fluorescence cuvette and microplate fluorimeters. There are several chromatography systems for HPLC and capillary GC analysis. This instrumentation is augmented by a range of modern facilities available through the Cool Climate Oenology and Viticulture Institute, which support work in biochemistry, especially work involving proteins, nucleic acids, yeasts and bacteria. Students should consult the Department Chair when planning years 3 and 4 of the BSc (Honours) and BSc with Major programs, or year 3 of the BSc (Pass) program. In addition to its own programs, the Chemistry department participates in combined major programs with six other departments/centres and is also a major participant in the Biochemistry, Biotechnology, Environment, and Oenology and Viticulture programs. |
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Year 1
Year 2
Year 3
Year 4
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Students admitted to the Chemistry Co-op program must follow an approved program pattern. The most common pattern is listed below. For other approved patterns, consult the Co-op Office. Year 1
Year 2
Spring/Summer Sessions:
Year 3 Fall Term:
Winter Term:
Year 4 Fall Term:
Winter Term:
Year 5
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Year 1
Spring/Summer Sessions:
Year 2
Spring/Summer Sessions:
Year 3 Fall Term:
Winter Term:
Year 4 Fall Term:
Winter Term:
Spring/Summer Sessions:
Year 5 Fall Term:
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BSc Honours in Chemistry: Environmental stream (Honours only) |
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The following has a biological content. A similar pattern with ERSC or GEOG courses replacing BIOL courses is possible. Consult the Chair. This program does not satisfy the requirements for membership in the Chemical Institute of Canada. Year 1
Year 2
Year 3
Year 4
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This program differs from the Honours program in that honours standing is not required for entry into year 4, and year 4 does not include the research project and thesis courses (CHEM 4F90 and 4F91). Combined majors should consult the Chair. Year 1
Year 2
Year 3
Year 4
Pass Program Satisfactory completion of the first three years of the Honours program entitles a student to apply for a Pass degree. Consult the Biochemistry calendar entry for a listing of courses and program requirements. Consult the Biotechnology calendar entry for a listing of courses and program requirements. |
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The Department of Chemistry and the Faculty of Education co-operate in offering two Concurrent BSc (Honours)/BEd programs and a BSc Integrated (Pass)/BEd program. The Chemistry BSc (Honours)/BEd programs combines the BA Honours program or BA Integrated Studies Honours program with the teacher education program for students interested in teaching at the Intermediate/Senior level (grades 7-12) and at the Junior/Intermediate level (grades 4-10). The BSc Integrated (Pass)/BEd combines the BSc Integrated Pass program with the teacher education program for students interested in teaching at the Junior/Intermediate level (grades 4-10). Refer to the Education - Concurrent BSc (Honours)/BEd (Intermediate/Senior), Education - Concurrent BSc Integrated Studies (Honours)/BEd (Junior/Intermediate) or Education-Concurrent BSc Integrated Studies (Pass)/BEd (Junior/Intermediate) program listings for further information. |
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Combined Honours and Pass programs can be taken in Chemistry/Biology, Chemistry/Computer Science (Honours only), Chemistry/Earth Sciences, Chemistry/Environment, Chemistry/Mathematics and Chemistry/Physics. In most of the combined major programs a research project must be successfully completed and a thesis written as part of the requirements for an Honours degree. |
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Honours Year 1
Year 2
Year 3
Year 4
Pass Satisfactory completion of the first three years of the Honours program entitles a student to apply for a Pass degree. |
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Honours Year 1
Year 2
Year 3
Year 4
Pass Satisfactory completion of the first three years of the Honours program entitles a student to apply for a Pass degree. |
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This agreement allows Brock to admit Mohawk graduates who have a minimum 78 percent overall average in the Chemical Engineering Technology Program to the Honours BSc program in Chemistry. Students automatically receive 6.5 credits towards the Honours BSc program in Chemistry. |
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Students in other disciplines may obtain a minor in chemistry within their degree program by completing the following courses with a minimum 60 percent average:
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Candidates with either an Honours or a (Pass) BA or a BSc degree in Chemistry, or equivalent, may apply to the Director of the Graduate Studies Office for entry into this program. Candidates holding a Pass degree will be required to take a qualifying year, similar to year 4 of the Honours program, before formally enrolling for the MSc degree. Candidates may be required to write Graduate Record Aptitude and Advanced Chemistry Examinations. Candidates with an Honours degree, or who have completed a qualifying year, require a minimum of one year of full-time study. The department offers a wide range of courses and research opportunities in analytical, inorganic, organic, physical and theoretical chemistry. For further information about the MSc program see the Graduate Calendar and the department's Graduate Studies brochure. |
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Note that not all courses are offered in every session. Refer to the applicable term timetable for details. # Indicates a cross listed course * Indicates a primary offering of a cross listed course |
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Students must check to ensure that prerequisites are met. Students may be deregistered, at the request of the instructor, from any course for which prerequisites and/or restrictions have not been met. Chemical Principles and Properties A chemical approach to describing the natural world. Molecular structure, shapes, and behaviour of molecules emphasizing organic compounds. Bonding and intermolecular interactions; the states of matter; solutions and their properties. Thermochemistry, entropy, free energy, chemical equilibrium, and reaction rates. Labs emphasize chemical syntheses, stoichiometry, and modern analytical techniques. Lectures, 3 hours per week; plus a minimum of six 3-hour labs per term. Prerequisite: a minimum 70 percent grade in OAC or Grade 12U chemistry (or equivalent course), CHEM 1P00, or permission of the Department. Introductory Chemistry Fundamental principles of chemistry. Topics include atomic structure and the periodic table, names and formulas of chemical compounds, principles of chemical bonding, types of chemical reactions, and basic chemical calculations. Tutorials emphasize the development and practice of problem solving skills. Lectures, 3 hours per week; lab, tutorial and problems solving session, 3 hours per week. Note: not open to students with 70 percent or greater in OAC or Grade 12U chemistry (or equivalent course). CHEM 1P00 is designed to assist those with insufficient background in chemistry to succeed in CHEM 1F92. Students with less than 70 percent in OAC or Grade 12U chemistry, or who have not taken an advanced high school chemistry course are allowed take CHEM 1F92 instead of CHEM 1P00 by permission of the Department if they pass a written test of basic chemistry knowledge, to be administered before classes begin. Chemical Principles and Properties General chemistry, stoichiometry, inorganic and organic structures and reactions. Laboratory work includes chemical purification and analysis. Lectures, 3 hours per week; plus a minimum of six 3-hour labs. Restriction: open to CAST majors. Introduction to Modern Physical Chemistry Phase equilibrium; gas phase kinetics; electronic structure of atoms and molecules; interaction of light with matter. Lectures, 3 hours per week; tutorial, 1 hour per week; plus a minimum of six 3-hour labs. Prerequisites: CHEM 1F92; MATH 1P01 and 1P02 (preferred), or MATH 1P97. Principles of Organic Chemistry I An introduction to the principles and techniques of organic chemistry; correlation of reactions and physical properties of organic compounds with structure and energetic concepts. Introduction to applications of spectroscopy in organic chemistry and biochemistry. Selected experiments in organic preparations and techniques. Lectures, lab, 6 hours per week. Prerequisite: CHEM 1F92. Principles of Organic Chemistry II Introduction to aromatic molecules and electrophilic aromatic substitution reactions. Chemistry of natural products, their origin and biological significance. Topics include concepts of carbonyl and carbohydrate chemistry, DNA and an introduction to amino acids and proteins. Selected experiments in organic synthesis, and characterization and analysis. Lectures, lab, 6 hours per week. Prerequisite: CHEM 2P20. Principles of Inorganic Chemistry A survey of the periodic table stressing periodicity of chemical behaviour. Chemistry and reactions in aqueous solutions; structure and bonding in simple compounds; applications to biological and environmental processes. Lectures, 3 hours per week; plus a minimum of six 3-hour labs. Prerequisite: CHEM 1F92. Introduction to Analytical Chemistry Introduction to separation methods such as chromatography, solvent extraction and precipitation; use of buffers for pH-control; statistical treatment of analytical data including normal distributions, significance testing and linear regression. Lectures, lab, 6 hours per week. Prerequisite: CHEM 1F92. Introduction to Biophysical Chemistry (also offered as BTEC 2P63) Physical chemistry as applied to biological sciences. Introductory thermodynamics, kinetics, equilibria, and transport phenomena as applied to proteins, biological membranes and other biological systems. Laboratory work includes kinetic measurements, equilibrium constant measurements and protein purification and characterization. Lectures, lab, 6 hours per week. Prerequisites: CHEM 1F92; MATH 1P01 and 1P02 (preferred), or MATH 1P97. Undergraduate Research Undergraduate research project carried out either in the department under the supervision of a faculty member or as an employee in a chemical industry or other suitable laboratory. Restriction: open to CHEM (single or combined) majors and permission of the Department. Note: if both CHEM 2P98 and CHEM 3P98 are taken, only one of these may be based on work done in the department. Structure and Reactivity of Organic Molecules Methods for functional group manipulation including oxidation, reduction and the use of protecting groups in organic chemistry. General methods for carbon-carbon bond formation emphasizing three dimensional structure and mechanism. Modern methods of asymmetric synthesis. Selected experiments in synthetic organic chemistry and the handling of air and water sensitive reagents. Lectures, lab, 6 hours per week. Prerequisite: CHEM 2P21 or permission of the Department. Note: CHEM 3P40 recommended. May be taken concurrently. Organic Reactions The chemistry of amines, heterocyclic and heteroaromatic compounds. Pericyclic reactions and reactive intermediates. Molecular rearrangements, peptide synthesis and protecting groups, design of organic synthesis. Introduction to organic photochemistry and the chemistry of carbenes. Lectures, lab, 6 hours per week. Prerequisite: CHEM 3P20. Transition Metal Chemistry Systematic inorganic and organometallic chemistry of the transition elements, with emphasis on structure, bonding and reactivity in inorganic and organometallic compounds. Selected experiments in inorganic and organometallic synthesis; use of modern structural methods for determination of composition, structure and bonding. Lectures, lab, 6 hours per week. Prerequisite: CHEM 2P32. Note: CHEM 3P40 recommended. May be taken concurrently. Main Group Inorganic Chemistry Continuation of CHEM 3P31 emphasizing the main group elements. Lectures, lab, 6 hours per week. Prerequisite: CHEM 3P31. Completion of this course will replace previous assigned grade in CHEM 3P30. Spectroscopic Techniques for Structure Elucidation Use of instrumental methods for the determination of structures of molecules. Techniques will include mass spectroscopy, nuclear magnetic resonance spectroscopy, dispersive and Fourier transform infrared spectroscopy, visible and UV spectroscopy, computerized data manipulation. Molecular modelling software may be included for three-dimensional visualization of complex molecules. Lectures, tutorial, 6 hours per week. Restriction: students must have a minimum of 9.0 overall credits. Prerequisite: CHEM 2P20. Instrumental Methods for Quantitative Analysis Use of instrumental methods for quantitative determination of elements and molecular species. Techniques include chromatography, atomic spectrometry, X-ray fluorescence spec-trometry, nuclear emission and neutron-activation analysis, introduction to electroanalytical techniques. Emphasis on sample preparation and cleanup and aspects of quality assurance/quality control. Lectures, lab, 6 hours per week. Restriction: students must have a minimum of 9.0 overall credits. Prerequisite: CHEM 2P42. Quantum Chemistry Schrodinger equation, solution of the harmonic oscillator problem, hydrogen atom, angular momentum theory, variational method with applications to atomic and molecular systems, molecular orbital theory and simple group theory. Introduction to FORTRAN 77. Lectures, 3 hours per week; lab, 2 hours per week; tutorial, 1 hour per week. Prerequisite: CHEM 2P12 or 2P63. Atomic and Molecular Structure and Spectroscopy Group theory and theory of electro-magnetic radiation and spectroscopic transitions. Rotational and vibrational spectroscopy (Microwave, IR, Raman); atomic and molecular electronic spectroscopy (UV/Visible); magnetic resonance (NMR, EPR); X-ray crystallography. Lectures, lab, 6 hours per week. Prerequisite: CHEM 3P51. Industrial Chemistry Principles and practice of industrial chemistry. A survey of the chemical industry, pollution control, plant design, corrosion and similar topics. Selected industrial processes will be discussed in detail. Tours of chemical plants and industrial laboratories. Lectures, 3 hours per week; seminars and plant tours, 3 hours per week. Prerequisite: one credit from CHEM 2P12, 2P20, 2P32, 2P42, 2P63. Bio-organic Chemistry (also offered as BTEC 3P62) Mechanistic description of the biosynthesis and metabolism of natural products including alkaloids, terpenes and acetate-derived compounds. Selected examples of biologically/medicinally active classes of natural products along with their physiological modes of activity. Lectures, lab, 6 hours per week. Prerequisite: CHEM 2P21. Protein and Nucleic Acid Chemistry (also offered as BTEC 3P63) Structure and chemistry of proteins and nucleic acids. Selected aspects of transcription, translation, protein folding, post-translational modification, targeting, synthesis and sequencing, and detection techniques. Lectures, lab, 6 hours per week. Prerequisite: CHEM 2P21. Undergraduate Research Undergraduate research project carried out either in the department under the supervision of a faculty member or as an employee in a chemical industry or other suitable laboratory. Restriction: open to CHEM (single or combined) majors with 9.0 overall credits and permission of the Department. Note: if both CHEM 2P98 and CHEM 3P98 are taken, only one of these may be based on work done in the department. Research Project Experimental or theoretical research to be carried out under faculty supervision. Restriction: open to CHEM (single or combined) and BCHM majors with approval to year 4 (honours) and permission of the Chair. Prerequisite: CHEM 3P40 or 3P41. Co-requisite: CHEM 4F91. Thesis The thesis incorporates the results of the research in CHEM 4F90 and forms the basis for a seminar to be presented by the student. Restriction: open to CHEM (single or combined) and BCHM majors with approval to year 4 (honours) and permission of the Chair. Prerequisite: CHEM 3P40 or 3P41. Co-requisite: CHEM 4F90. Special Topics Tutorials, seminars, special projects or directed readings in an area of chemistry. Lectures/ seminar/ tutorial, 3 hours per week. Restriction: open to CHEM (single or combined) majors with a minimum of 14.0 overall credits and permission of the Chair. Statistical Thermodynamic in Chemistry and Biology Ensembles, entropy, free energy, statistical mechanics of simple gases and solids, heat capacity, chemical equilibrium, substrate binding, water as a solvent, and polymers and biopolymers. Lectures, seminar, 3 hours per week. Prerequisite: CHEM 3P51. Co-requisite: CHEM 3P53. Biophysical Photochemistry Principles of light induced processes such as electron, energy and signal transfer and their role in biological systems. Marcus theory, Dexter and Foerster mechanisms of energy transfer. The optical and magnetic resonance spectroscopy of excited states. Lectures, 3 hours per week. Prerequisite: CHEM 3P40, 3P53 or permission of the instructor. Computational Chemistry: Applications in Biotechnology (also offered as BTEC 4P18) Structure-based drug design, molecular modelling, conformational search techniques, secondary and tertiary protein structure prediction, quantitative structure activity relationships and bioinformatics. Lectures, 3 hours per week. Restriction: students must have a minimum of 13.5 overall credits. Prerequisite: CHEM 2P12 or 2P63. Organic Reactions and Synthesis The disconnection approach to organic synthesis. Problems of chemo-, regio- and stereo-selectivity. Appreciation of elaborate syntheses. Synthetic organic chemistry topics from the recent literature. Lectures, seminar, 3 hours per week. Prerequisite: CHEM 3P21. Organic Reactions and Mechanisms Topics include conformational analysis, introduction to transition state theory and the description of stereo and electronic control in organic reactions. Pertinent applications will be taken from the recent literature. Lectures, seminar, 3 hours per week. Prerequisite: CHEM 3P21. Organometallics in Organic Synthesis Use of organometallic reagents for organic transformations. Metalation and trans-metalation using organolithium, magnesium, cerium and zinc reagents; stable precursors and reactive intermediates in transition metal catalyzed organic reactions employing palladium, nickel, ruthenium, and other metals. Topics from recent literature involving applications to organic synthesis, emphasizing stereoselectivity. Lectures, seminar, 3 hours per week. Prerequisite: CHEM 3P21. Enzyme and Co-enzyme Mechanisms (also offered as BTEC 4P27) Hydrolytic and other processes catalyzed by enzymes lacking non-protein prosthetic groups; transferase reactions involving biotin, pyridoxal phosphate, thiamine pyrophosphate, folic acid and cobalamin; oxidation mechanisms involving pyridine nucleotides, flavoenzymes, hydroperoxidases and oxgenases. Lectures, seminar, 3 hours per week. Prerequisites: CHEM 2P21, BCHM 3P01and 3P02. Bio-inorganic Chemistry Principles governing selection, uptake, storage, transport, and role of metal ions in biological processes. Topics include electron-transfer systems, substrate binding and activation by nonredox enzymes, metal-containing drugs, and biomineralization. Lectures, seminar, 3 hours per week. Restriction: students must have a minimum of 12.0 overall credits. Prerequisites: CHEM 2P21 and 2P32. Enviro-Analytical Chemistry Chemical speciation studied by a variety of modern analytical techniques. Transport and fate of various compounds and elements in the environment. Lectures, seminar, 3 hours per week. Prerequisite: CHEM 3P41. Biophysical Techniques (also offered as BCHM 4P67 and BTEC 4P67) Modern instrumental methods of biotechnology emphasizing understanding theory. Development of newer technologies which utilize biological components. Topics include optical, X-ray and NMR techniques, separation techniques, hybridization assays, immunoassays, biosensors and mass spectral techniques; membrane chemistry. Lectures, seminar, 3 hours per week. Prerequisites: CHEM 2P21 and 2P63 or permission of the instructor. Biotransformations (also offered as BTEC 4P68) The organic reactions carried out by isolated enzymes, fungal cultures and bacteria. The production of pharmaceutical, agricultural and industrial chemicals by biological processes. Lectures, 3 hours per week. Prerequisite: one of CHEM 3P20, 3P62, 3P63 or permission of the instructor. Library Research and Seminar Detailed study of the scientific literature under faculty supervision. Restriction: open to students in the BSc with a Major in Chemistry program with a minimum of 15.0 overall credits or permission of the Department. Note: the results of the study will be written up in a major essay and presented as a formal seminar. |
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Work Placement I First co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. Work Placement II Second co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. Work Placement III Third co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. Work Placement IV Optional Co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. Work Placement V Optional Co-op work placement (4 months) with an approved employer. Restriction: open to CHEM Co-op students. |
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Science and Society For non-science majors, basic questions and problems in understanding the nature of science and technology and their impact on contemporary society. Some questions addressed: how are scientific theories formulated? What is pollution? What is the relation of science to ethics and public policy? Lectures, 3 hours per week; seminar, 1 hour, alternate weeks. Note: co-ordinated through the Department of Chemistry. |
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Co-op Training and Development Framework for the development of learning objectives for individual work terms, for students in the co-op programs in the Faculty of Mathematics and Science. Includes orientation to the co-op experience, goal setting, career planning, resume preparation and interview skills preparation. Lectures, presentations, site visits, 2 hours per week. Restriction: open to Science Co-op students. Note: see Director of Co-op Programs Office. |
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2005-2006 Undergraduate Calendar
Last updated: June 28, 2005 @ 02:26PM