Chemistry Courses

CHEM 0N00
Work Placement
Optional Co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.

CHEM 0N01
Work Placement I
First co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.

CHEM 0N02
Work Placement II
Second co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.

CHEM 0N03
Work Placement III
Third co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.

CHEM 0N04
Work Placement
Optional Co-op work placement (4 months) with an approved employer.
Restriction: open to CHEM Co-op students.

CHEM 1F92
Chemical Principles and Properties
A chemical approach to describing the natural world. Molecular structure, shapes, and behaviour of molecules, with emphasis on organic compounds. Bonding and intermolecular interactions; the states of matter; solutions and their properties. Thermochemistry, entropy, free energy, chemical equilibrium, and reaction rates. Labs emphasize chemical syntheses, stoichiometry, and modern analytical techniques.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisite: a minimum 70 percent grade in OAC chemistry (or equivalent course) or CHEM 1P00, or permission of the department.

CHEM 1P00
Introductory Chemistry
Fundamental principles of chemistry. Topics include atomic structure and the periodic table, names and formulas of chemical compounds, principles of chemical bonding, types of chemical reactions, and basic chemical calculations. Tutorials emphasize the development and practice of problem solving skills.
Lectures, 3 hours per week; lab, tutorial and problems solving session, 3 hours per week.
Note: not open to students with 70 percent or greater in OAC chemistry or equivalent. CHEM 1P00 is designed to assist those with insufficient background in chemistry to succeed in CHEM 1F92. Students with less than 70 percent in OAC chemistry, or who have not taken an advanced high school chemistry course are allowed take CHEM 1F92 instead of CHEM 1P00 by permission of the Department if they pass a written test of basic chemistry knowledge, to be administered before classes begin.

CHEM 1P81
Introduction to Modern Chemistry II
Gas laws, thermochemistry, solutions, chemical equilibria and kinetics. Problem solving is stressed. Laboratory work includes chemical analysis and synthesis and experiments illustrating lecture topics.
Lectures, 3 hours per week; seminar, lab, 3 hours per week.
Prerequisite: CHEM 1P90 ( or 1P80).
Completion of this course will replace previous assigned credit in CHEM 1P91.

CHEM 1P90
Chemical Principles and Properties
General chemistry, stoichiometry, inorganic and organic structures and reactions. Laboratory work includes chemical purification and analysis.
Lectures, 3 hours per week; lab, 3 hours per week.
Restriction: open to CSDT majors.
Completion of this course will replace previous assigned grade in CHEM 1P80.

CHEM 2P12
Introduction to Modern Physical Chemistry
Phase equilibrium; gas phase kinetics; electronic structure of atoms and molecules; interaction of light with matter.
Lectures, 3 hours per week; tutorial, 1 hour per week; lab, 3 hours alternating weeks.
Prerequisites: CHEM 1F92 (1P80 and 1P81 or 1P90 and 1P91); MATH 1P01 and 1P02 (preferred), or MATH 1P97.

CHEM 2P20
Principles of Organic Chemistry
An introduction to the principles and techniques of organic chemistry; correlation of reactions and physical properties of organic compounds with structure and energetic concepts. Laboratory work includes organic preparations and techniques.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisites: CHEM 1F92 (1P80 and 1P81 or 1P90 and 1P91).

CHEM 2P21
Principles of Bio-organic Chemistry
Organic chemistry of selected groups of natural products; their biological origin and significance. Introduction to applications of spectroscopy in organic chemistry and biochemistry. Laboratory work includes organic syntheses and characterization and organic analysis.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisite: CHEM 2P20.

CHEM 2P32
Principles of Inorganic Chemistry
A survey of the periodic table stressing periodicity of chemical behaviour. Chemistry and reactions in aqueous solutions; structure and bonding in simple compounds; applications to biological and environmental processes.
Lectures, 3 hours per week; lab, 3 hours alternating weeks.
Prerequisites: CHEM 1F92 (1P80 and 1P81 or 1P90 and 1P91).

CHEM 2P42
Introduction to Analytical Chemistry
Introduction to separation methods such as chromatography, solvent extraction and precipitation; use of buffers for pH-control; statistical treatment of analytical data including normal distributions, significance testing and linear regression.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisites: CHEM 1F92 (1P80 and 1P81 or 1P90 and 1P91).

CHEM 2P63
Introduction to Biophysical Chemistry
(also offered as BTEC 2P63)
Physical chemistry as applied to biological sciences. Introductory thermodynamics, kinetics, equilibria and transport phenomena as applied to proteins, biological membranes and other biological systems. Laboratory work includes kinetic measurements, equilibrium constant measurements and protein purification and characterization.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisites: CHEM 1F92 (1P80 and 1P81 or 1P90 and 1P91); MATH 1P01 and 1P02 (preferred), or MATH 1P97.

CHEM 2P98
Undergraduate Research
Undergraduate research project carried out either in the department under the supervision of a faculty member or as an employee in a chemical industry or other suitable laboratory.
Restriction: open to CHEM (single or combined) majors and permission of the department.
Note: if both CHEM 2P98 and CHEM 3P98 are taken, only one of these may be based on work done in the department.

CHEM 3P20
Structure and Reactivity of Organic Molecules
Basic stereochemical principles. Methods for functional group manipulation including oxidation, reduction and the use of protecting groups in organic chemistry. General methods for carbon-carbon bond formation emphasising three dimensional structure and mechanism. Modern methods of asymmetric synthesis. Laboratory work includes selected experiments in synthetic organic chemistry and the handling of air and water sensitive reagents.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisite: CHEM 2P20 or permission of the department.
Note: CHEM 3P40 recommended. May be taken concurrently.

CHEM 3P21
Organic Reactions
The chemistry of acyclic, cyclic and heterocyclic compounds, reactive intermediates, design of organic synthesis, molecular rearrangements, free radical chemistry; introduction to organic photochemistry and electrochemistry.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisite: CHEM 3P20.

CHEM 3P31
Transition Metal Chemistry
Systematic inorganic and organometallic chemistry of the transition elements, with emphasis on structure, bonding and reactivity in inorganic and organometallic compounds. Selected experiments in inorganic and organometallic synthesis; use of modern structural methods for determination of composition, structure and bonding.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisite: CHEM 2P32.
Note: CHEM 3P40 recommended. May be taken concurrently.

CHEM 3P32
Main Group Inorganic Chemistry
A continuation of CHEM 3P31, emphasizing the main group elements.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisite: CHEM 3P31.
Completion of this course will replace previous assigned grade in CHEM 3P30.

CHEM 3P40
Spectroscopic Techniques for Structure Elucidation
The use of instrumental methods for the determination of structures of molecules. Techniques will include mass spectro-scopy, nuclear magnetic resonance spectroscopy, dispersive and Fourier transform infrared spectroscopy, visible and UV spectroscopy, computerized data manipulation. Molecular modelling software may be included for three-dimensional visualization of complex molecules.
Lectures, 3 hours per week; tutorial, 3 hours per week.
Restriction: students must have a minimum of 9.0 overall credits.
Prerequisite: CHEM 2P20.

CHEM 3P41
Instrumental Methods for Quantitative Analysis
The use of instrumental methods for quantitative determination of elements and molecular species. Techniques include chromatography, atomic spec-trometry, X-ray fluorescence spec-trometry, nuclear emission and neutron-activation analysis, introduction to electroanalytical techniques. Emphasis on sample preparation and cleanup and aspects of quality assurance/quality control.
Lectures, 3 hours per week; lab, 3 hours per week.
Restriction: students must have a minimum of 9.0 overall credits.
Prerequisite: CHEM 2P42.

CHEM 3P51
Quantum Chemistry
Schrodinger equation, solution of the harmonic oscillator problem, hydrogen atom, angular momentum theory, variational method with applications to atomic and molecular systems, molecular orbital theory and simple group theory. Introduction to FORTRAN 77.
Lectures, 3 hours per week; lab, 2 hours per week; tutorial, 1 hour per week.
Prerequisite: CHEM 2P12 or 2P63.

CHEM 3P53
Atomic and Molecular Structure and Spectroscopy
Group theory and theory of electro-magnetic radiation and spectroscopic transitions. Rotational and vibrational spectroscopy (Microwave, IR, Raman); atomic and molecular electronic spec-troscopy (UV/Visible); magnetic resonance (NMR, EPR); X-ray crys-tallography.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisite: CHEM 3P51.

CHEM 3P60
Industrial Chemistry
Principles and practice of industrial chemistry. A survey of the chemical industry, pollution control, plant design, corrosion and similar topics. Selected industrial processes will be discussed in detail. Tours of chemical plants and industrial laboratories.
Lectures, 3 hours per week; seminar and plant tours, 3 hours per week.
Prerequisite: one credit from CHEM 2P12, 2P20, 2P32, 2P42, 2P63.

CHEM 3P62
Bio-organic Chemistry
(also offered as BTEC 3P62)
The biosynthesis of the natural products of secondary metabolism. Introduction to the use of enzymes and other biological reagents in organic synthesis.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisite: CHEM 2P21.

CHEM 3P63
Protein and Nucleic Acid Chemistry
(also offered as BTEC 3P63)
Structure and chemistry of proteins and nucleic acids. Selected aspects of transcription, translation, protein folding, post-translational modification, targeting, synthesis and sequencing, and detection techniques.
Lectures, 3 hours per week; lab, 3 hours per week.
Prerequisite: CHEM 2P21.

CHEM 3P98
Undergraduate Research
Undergraduate research project carried out either in the department under the supervision of a faculty member or as an employee in a chemical industry or other suitable laboratory.
Restriction: open to CHEM (single or combined) majors with 9.0 overall credits and permission of the department.
Note: if both CHEM 2P98 and CHEM 3P98 are taken, only one of these may be based on work done in the department.

CHEM 4F90
Research Project
Experimental or theoretical research to be carried out under faculty supervision.
Restriction: open to CHEM (single or combined) and BCHM majors with approval to year 4 (honours) and permission of the Chair.
Prerequisite: CHEM 3P40 or 3P41.
Co-requisite: CHEM 4F91.

CHEM 4F91
Thesis
The thesis incorporates the results of the research in CHEM 4F90 and forms the basis for a seminar to be presented by the student.
Restriction: open to CHEM (single or combined) and BCHM majors with approval to year 4 (honours) and permission of the Chair.
Prerequisite: CHEM 3P40 or 3P41.
Co-requisite: CHEM 4F90.

CHEM 4P14
Statistical Thermodynamics
Systems of independent particles, chemical equilibrium, partition functions for atoms and molecules, nuclear spin statistics, fluctuations, thermodynamic properties of crystals, real gases, metals.
Lectures, seminar, 3 hours per week.
Prerequisite: CHEM 3P51.
Co-requisite: CHEM 3P53.

CHEM 4P15
Principles of Physical Polymer Chemistry
Techniques used in characterization of such polymer properties as molecular weight, configuration and conformation. Structure-property relationships inclu-ding an analysis of the amorphous and crystalline states. Liquid crystalline polymers, polymer blends and medical polymers.
Lectures, 3 hours per week.
Restriction: students must have a minimum of 13.5 overall credits.
Prerequisite: CHEM 2P12 or 2P63.

CHEM 4P16
Physical Chemistry of Surfaces
Introduction to basic concepts of the physical chemistry of surfaces including surface tension, wetting, adhesion, adsorption and binding, and catalysis. Examination of modern methods of analysis of surface composition, both chemical and physical.
Lectures, 3 hours per week.
Restriction: Students must have a minimum of 13.5 overall credits.
Prerequisite: CHEM 2P12 or 2P63.

CHEM 4P17
Biophysical Photochemistry
Principles of light induced processes such as electron, energy and signal transfer and their role in biological systems. Marcus theory, Dexter and Foerster mechanisms of energy transfer. The optical and magnetic resonance spectroscopy of excited states.
Lectures, 3 hours per week.
Prerequisite: CHEM 3P40 or 3P53 or permission of the instructor.

CHEM 4P18
Computational Chemistry: Applications in Biotechnology
(also offered as BTEC 4P18)
Structure-based drug design, molecular modelling, conformational search techniques, secondary and tertiary protein structure prediction, quantitative structure activity relationships and bioinformatics.
Lectures, 3 hours per week.
Restriction: students must have a minimum of 13.5 overall credits.
Prerequisites: CHEM 2P12 or 2P63.

CHEM 4P21
Organic Reactions and Synthesis
The disconnection approach to organic synthesis. Problems of chemo-, regio- and stereo-selectivity. Appreciation of elaborate syntheses. Synthetic organic chemistry topics from the recent literature.
Lectures, seminar, 3 hours per week.
Prerequisite: CHEM 3P21.

CHEM 4P22
Organic Reactions and Mechanisms
Topics include conformational analysis, introduction to transition state theory and the description of stereo and electronic control in organic reactions. Pertinent applications will be taken from the recent literature.
Lectures, seminar, 3 hours per week.
Prerequisite: CHEM 3P21.

CHEM 4P27
Enzyme and Co-enzyme Mechanisms
(also offered as BTEC 4P27)
Hydrolytic and other processes catalyzed by enzymes lacking non-protein prosthetic groups; transferase reactions involving biotin, pyridoxal phosphate, thiamine pyrophosphate, folic acid and cobalamin; oxidation mechanisms involving pyridine nucleotides, flavoenzymes, hydroperoxidases and oxgenases.
Lectures, seminar, 3 hours per week.
Prerequisites: CHEM 2P21, BCHM 3P01and 3P02.

CHEM 4P40
Scientific Instrumentation
Review of the use of electronic compo-nents and circuits for measurements and control; analog and digital measurements; instrument optics. Application to spectroscopic, electrochemical and other scientific instrumentation used for analysis, measurement or control.
Lectures, 3 hours per week.
Prerequisite: CHEM 3P40 or 3P41 or permission of the instructor.

CHEM 4P47
Nuclear Magnetic Resonance (NMR) Spectroscopy
Applications of high-resolution NMR spectroscopy to chemical systems. Theory of chemical shifts, coupling constants and relaxation times; instrumentation, including pulse and Fourier transform techniques; structure determination by NMR; two-dimensional NMR; chemical exchange effects.
Lectures, 3 hours per week.
Prerequisite: CHEM 3P40 or permission of the instructor.

CHEM 4P48
Mass Spectroscopy
The theory and practice of modern mass spectroscopy applied to organic, inorganic and organometallic systems; systematic interpretation of organic mass spectra; high resolution mass spectra; GC/MS; HPLC/MS; new ionization methods; metastable ions; computerized mass spectrometry.
Lectures, 3 hours per week.
Prerequisite: CHEM 3P40 or permission of the instructor.

CHEM 4P67
Biophysical Techniques
(also offered as BCHM 4P67 and BTEC 4P67)
Modern instrumental methods of biotechnology emphasizing under-standing theory. Development of newer technologies which utilize biological components. Topics include optical, X-ray and NMR techniques, separation techniques, hybridization assays, immunoassays, biosensors and mass spectral techniques; membrane chemistry.
Lectures, seminar, 3 hours per week.
Prerequisites: CHEM 2P21 and 2P63 or permission of the instructor.

CHEM 4P68
Biotransformations
(also offered as BTEC 4P68)
The organic reactions carried out by isolated enzymes, fungal cultures and bacteria. The production of pharmaceutical, agricultural and industrial chemicals by biological processes.
Lectures, 3 hours per week.
Prerequisite: one of CHEM 3P20, 3P62, 3P63 or permission of the instructor.

CHEM 4P92
Library Research and Seminar
Detailed study of the scientific literature under faculty supervision.
Restriction: open to students in the BSc with a Major in Chemistry program with a minimum of 15.0 overall credits or permission of the Department.
Note: the results of the study will be written up in a major essay and presented as a formal seminar.

CHEM 4V10-4V13
Special Topics in Physical Chemistry
Selected topics in advanced physical chemistry.
Prerequisite: CHEM 3P51 and 3P53.

CHEM 4V23-4V26
Special Topics in Organic Chemistry
Selected topics in advanced organic chemistry.
Prerequisite: CHEM 3P20 and 3P21.

CHEM 4V30-4V35
Special Topics in Inorganic Chemistry
Selected topics in advanced inorganic chemistry.
Prerequisites: CHEM 3P30 and 3P31.

CHEM 4V41-4V45
Special Topics in Analytical Chemistry
Lectures, seminar, 3 hours per week.
Prerequisite: CHEM 3P41.