Researchers at Brock and McMaster universities have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and to improve access to diagnostic testing.<\/p>\n
The device works much like the monitors that diabetics use to test their blood-sugar levels and could be used in a medical clinic or at home, all without lab work, greatly simplifying the process for testing blood for cancer\u2019s signature.<\/p>\n
A user would mix a droplet of blood in a vial of reactive liquid, then place the mixture onto a strip and insert it into a reader. In minutes, the device would measure an antigen that indicates the degree to which cancer is present.<\/p>\n
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The prototype is expected to improve access to diagnostic testing.<\/p><\/div>\n
The prototype has been designed to monitor prostate specific antigen (PSA) and the technology can readily be adapted to measure other markers, depending on the form of cancer or other chronic disease.<\/p>\n
The ability to collect such information at home would make the daily lives of patients much easier while also generating accurate, shareable, up-to-the-minute results to guide their doctors in shaping care and treatment \u2013 all at a lower cost to the health-care system.<\/p>\n
The device would also allow patients to continue to monitor their health after treatment.<\/p>\n
The prototype was created by a research collaboration led by Brock\u2019s Feng Li, an associate professor of Chemistry who leads a bioanalytical chemistry lab, and McMaster\u2019s Leyla Soleymani, a biomedical engineer and Canada Research Chair in Miniaturized Biomedical Devices.<\/p>\n
Li\u2019s team (also including Guan Wang) created the technology that analyzes the sample, while Soleymani\u2019s team (also including Sarah Traynor and Richa Pandey) was responsible for the hardware, including the chip that reads the sample.<\/p>\n
\u201cOnce commercialized, this device will be a paradigm shift for cancer diagnosis and prognosis,\u201d Li says. \u201cSince this device is a lot more accessible and user-friendly than conventional technologies, patients will be more willing to use it, which can improve clinical outcomes and save lives.\u201d<\/p>\n
This is \u201canother step toward truly personalized medicine,\u201d Soleymani says. \u201cWe\u2019re getting away from centralized, lab-based equipment for this kind of testing. This would make monitoring much more accessible and cut down on the number of times patients need to leave home to provide blood samples.\u201d<\/p>\n
The researchers\u2019 proof-of-concept work is described in an article<\/a> published in the journal Angewandte Chemie<\/em>. The invention will need to be tested more broadly before earning the regulatory approvals that would permit commercial manufacturing.<\/p>\n","protected":false},"excerpt":{"rendered":"Researchers at Brock and McMaster universities have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and to improve access to diagnostic testing.<\/p>\n","protected":false},"author":1,"featured_media":68474,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7,3319,41,1,4,5],"tags":[1291,3367,48,4243,9555,470,3325],"_links":{"self":[{"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/posts\/68473"}],"collection":[{"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/comments?post=68473"}],"version-history":[{"count":1,"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/posts\/68473\/revisions"}],"predecessor-version":[{"id":68476,"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/posts\/68473\/revisions\/68476"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/media\/68474"}],"wp:attachment":[{"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/media?parent=68473"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/categories?post=68473"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/brocku.ca\/brock-news\/wp-json\/wp\/v2\/tags?post=68473"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}