Associate Professor, Health Sciences
Paul J. LeBlanc is an Associate Professor in the Department of Health Sciences. Paul completed his Ph.D. at McMaster University and his undergraduate studies and M.Sc. at the University of Guelph. Paul’s research interests lie within musculoskeletal health and the role of the cellular membrane in mediating health and disease of muscle and bone. Paul has reviewed grants for various national and international funding agencies, including NSERC, CIHR, CFI, and Barth Syndrome Foundation.
- Membrane structure-protein function relationship
- Skeletal muscle metabolic and functional adaptation
- Role of phospholipids in mediating bone (osteoporosis) and muscle (muscular dystrophy) diseases.
- American Physiological Society
Fajardo, VA, JS Mikhaeil, C Leveille, C Saint, PJ LeBlanc. 2017. Cardiolipin content, linoleic acid composition, and tafazzin expression in response to skeletal muscle overload and unload stimuli. Sci Rep [accepted SREP-16-46372B].
Longo AB, PJ Sullivan, SJ Peters, PJ LeBlanc, GR Wohl, WE Ward. 2017. Lifelong intake of flaxseed or menhaden oil to provide varying n-6 to n-3 PUFA ratios modulate bone microarchitecture during growth, but not after OVX in Sprague-Dawley rats. Mol Nutr Food Res [epub ahead of print].
Sacco SM, C Saint, PJ LeBlanc, WE Ward. 2017. Maternal consumption of hesperidin and naringin flavones exert transient effects to tibial bone structure in female CD-1 offspring. Nutrients 9:E250.
Fajardo, VA, N Trojanowski, LM Castelli, PM Miotto, F Amoye, WE Ward, AR Tupling, PJ LeBlanc. 2017. Saturation of SERCA’s lipid annulus may protect against its thermal inactivation. Biochem Biophys Res Commun 484:456.
Sacco SM, C Saint, AB Longo, CB Wakefield, PL Salmon, PJ LeBlanc, WE Ward. 2017. Repeated irradiation from micro-computed tomography scanning at 2, 4, and 6 months of age does not induce damage to tibial bone microstructure in male and female CD-1 mice. Bonekey Rep 6:855.
Snook LA, RE MacPherson, CM Monaco, S Frendo-Cumbo, L Castellani, WT Peppler, ZG Anderson, SL Buzelle, PJ LeBlanc, GP Holloway, DC Wright. 2016. Prior exercise training blunts short term high fat diet induced weight gain. Am J Physiol 311:R315.
Miotto, PM, LM Castelli, F Amoye, WE Ward, PJ LeBlanc. 2015. High saturated fat diet alters the lipid composition of triacylglycerol and polar lipids in the femur of dam and offspring rats. Lipids 50:605.
Fajardo, VA, L McMeekin, C Saint, PJ LeBlanc. 2015. Cardiolipin linoleic acid content and mitochondrial cytochrome c oxidase activity are associated in rat skeletal muscle. Chem Phys Lipids 187:50.
Ramos, SV, PC Turnbull, RE MacPherson, PJ LeBlanc, WE Ward, SJ Peters 2015. Changes in mitochondrial PLIN3 and PLIN5 protein content in rat skeletal muscle following endurance training and acute stimulated contraction. Exp Physiol 100:450.
MacPherson, RE, LM Castelli, PM Miotto, S Frendo-Cumbo, A Milburn, BD Roy, PJ LeBlanc, WE Ward, SJ Peters. 2015. A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood. Lipids 50:205.
Hajna, S, PJ LeBlanc, BE Faught, AT Merchant, J Cairney, J Hay, J Liu. 2014. Association between family eating behaviours and body composition in peri-adolescence: Results from a community-based study of school-aged children. Can J Public Health 105:e15.
Herbst, EA, RE Macpherson, PJ LeBlanc, BD Roy, NH Jeoung, RA Harris, SJ Peters. 2014. Pyruvate dehydrogenase kinase-4 contributes to the recirculation of gluconeogenic precursors during post-exercise glycogen recovery. Am J Physiol 306:R102.
Miotto, PM, LM Castelli, F Amoye, PJ LeBlanc, SJ Peters, BD Roy, WE Ward. 2013. Maternal high fat feeding does not have long-lasting effects on body composition and bone health in female and male wistar rat offspring at young adulthood. Molecules 18:15094.
Farlinger, CM, AJ Lui, RC Harrison, PJ LeBlanc, SJ Peters, BD Roy. 2013. Extracellular hyperosmotic stress stimulates glucose uptake in incubated fast-twitch rat skeletal muscle. Appl Physiol Nutr Metab 38:605.
Fajardo, VA, L McMeekin, A Basic, G Lamb, R Murphy, PJ LeBlanc. 2013. Isolation of sarcolemmal plasma membranes by mechanically skinning rat skeletal muscle fibers for phospholipid analysis. Lipids 48:421.
Hajna, S, J Liu, PJ LeBlanc, BE Faught, AT Merchant, J Cairney, J Hay. 2012. Association between body composition and conformity to the recommendations of Canada’s Food Guide and the Dietary Approaches to Stop Hypertension (DASH) diet in peri-adolescence. Public Health Nutr 15:1890.
Holloway, GP, VA Fajardo, L McMeekin, PJ LeBlanc. 2012. Unsaturation of mitochondrial membrane lipids is related to palmitate oxidation in subsarcolemmal and intermyofibrillar mitochondria. J Mem Biol 245:165.
Herbst, EA, EC Dunford, RA Harris, R Vandenboom, PJ LeBlanc, BD Roy, NH Jeoung, SJ Peters. 2012. Role of pyruvate dehydrogenase kinase 4 in regulating PDH activation during acute muscle contraction. Appl Physiol Nutr Metab 37:48.
- Nutrition in Health Care
- Nutrition and Health